Alexander the Great in Fausset's Bible Dictionary

1. ALEXANDER THE GREAT. Born at Pella, 356 B.C., son of Philip, king of Macedon; not named, but described prophetically: "an he-goat" )symbol of ogility, the Graeco- Macedonian empire) coming from the W. on the face of the whole earth and not touching the ground (implying the incredible swiftness of his conquests); and the goat had A NOTABLE HORN (Alexander) between his eyes, and he came to the ram that had two horns (Media and Persia, the second great world kingdom, the successor of Babylon; under both Daniel prophesied long before the rise of the Macedon-Greek kingdom) standing before the river (at the river Granicus Alexander gained his first victory over Darius Codomanus, 334 B.C.) and ran unto him in the fury of his power, moved with choler against him (on account of the Persian invasions of Greece and cruelties to the Greeks), and smote the ram and broke his two horns; and there was no power in the ram to stand before him; but he cast him down to the ground and stamped upon him, and there was none that could deliver the ram out of his hand: therefore the he-goat waxed very great, and when he was strong the great horn was broken, and for it came up four notable ones toward the four winds of heaven" (Daniel 8:5-8)...

Link: https://bible-history.com/faussets/A/Alexander/