Antioch

(1.) In Syria, on the river Orontes, about 16 miles from the
Mediterranean, and some 300 miles north of Jerusalem. It was the
metropolis of Syria, and afterwards became the capital of the
Roman province in Asia. It ranked third, after Rome and
Alexandria, in point of importance, of the cities of the Roman
empire. It was called the "first city of the East." Christianity
was early introduced into it (Acts 11:19, 21, 24), and the name
"Christian" was first applied here to its professors (Acts
11:26). It is intimately connected with the early history of the
gospel (Acts 6:5; 11:19, 27, 28, 30; 12:25; 15:22-35; Gal. 2:11,
12). It was the great central point whence missionaries to the
Gentiles were sent forth. It was the birthplace of the famous
Christian father Chrysostom, who died A.D. 407. It bears the
modern name of Antakia, and is now a miserable, decaying Turkish
town. Like Philippi, it was raised to the rank of a Roman
colony. Such colonies were ruled by "praetors" (R.V. marg., Acts
16:20, 21).

(2.) In the extreme north of Pisidia; was visited by Paul and
Barnabas on the first missionary journey (Acts 13:14). Here they
found a synagogue and many proselytes. They met with great
success in preaching the gospel, but the Jews stirred up a
violent opposition against them, and they were obliged to leave
the place. On his return, Paul again visited Antioch for the
purpose of confirming the disciples (Acts 14:21). It has been
identified with the modern Yalobatch, lying to the east of
Ephesus.